Category: NIH

Volume 403, Issue 10427  ♦  17 February 2024

 

PROFILE  Dr. Monica Bertagnolli, Director of the National Institutes of Health  

“I imagine a health-care system where clinical decisions are informed in real time by current research data,” the new National Institutes of Health director tells The Lancet. “And one where patients have the opportunity to both contribute their data for research and get back research results so that they can experience the best that science has to offer.” [Susan Jaffe reports here.]…

Biden’s science adviser resigns over bullying

Volume 399, Issue 10326
19 February 2022

 

WORLD REPORT   Experts say that Eric Lander’s resignation should not affect the President’s plans to reboot the cancer moonshot project. Susan Jaffe reports.…

$6·5 billion proposed for new US health research agency

Volume 397, Issue 10288
22 May 2021

WORLD REPORT The Advanced Research Projects Agency for Health would fund high-risk, high-reward medical research, but its short-term planning could stymie basic research. Susan Jaffe reports.

During his first address to a joint session of Congress last month, US President Joe Biden drew little applause from Republicans in the physically distanced, masked audience. A rare exception to their steadfast silence came when he unveiled an ambitious plan to eradicate cancer.

To help reach this goal, Biden would establish a new biomedical research agency within the National Institutes of Health (NIH) called the Advanced Research Projects Agency for Health (ARPA-H). The agency would provide a fast track for transforming basic science into real-world applications. [Continued here.]

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US election 2020: research and health institutions

Volume 396, Number 10259

24 October 2020

 

WORLD REPORT   How will the NIH, CDC, and FDA change if President Donald Trump wins a second term or if his Democratic challenger, Joe Biden, defeats him? Susan Jaffe reports from Washington, DC. 

Whoever wins the presidency needs to “restore the CDC and improve it by letting [scientists] know that they will have an opportunity to do the best science and make the best recommendations…” says James Curran, dean of the Rollins School of Public Health at Emory University in Atlanta. [Continued here.]…

State Says Hospitals Must Allow Support Person at Births

FAMILIES    |    THE CITY    |    March 28, 2020     
The state Department of Health has toughened up its message to hospitals that have been telling pregnant women they can’t bring a partner or other support person into the delivery room because of coronavirus concerns. The new visitation policy’s boldface wording, issued late Friday, appears to leave little open to interpretation.
It “requires hospitals to allow one support person in labor and delivery settings if the patient so desires and two designated support persons in pediatric settings, provided that only one is present at a time.”
…The update reverses visitor bans announced earlier this week by New York-Presbyterian and Mount Sinai Health System in response to the coronavirus crisis. Other hospital systems had been expected to adopt similar procedures. [continued here]
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Decisions to be made on US gun violence research funds

Volume 395       Number 10222     8 February 2020   
WORLD REPORT  The National Institutes of Health and the Centers for Disease Control and Prevention will decide how to spend new federal funds later this year. Susan Jaffe reports from Washington, DC.
After a hiatus of more than two decades, Congress and President Donald Trump agreed to add funding for gun violence research to the federal budget in December. With grants expected to be awarded in September, the priorities for research and its potential impact are crucial for halting the US’s record-breaking gun-related death toll. [Continued here.]   
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Trump administration limits fetal tissue research

Volume 393    Number 10189         15 June 2019   
WORLD REPORT    The move could threaten medical research advances, say scientists, as acquisition of new fetal tissue for research is substantially hindered. Susan Jaffe reports.              

“Many discoveries now in clinical practice and wide research use have come from human fetal tissue”, said Irving Weissman, director of the Stanford Institute for Stem Cell Biology and Regenerative Medicine. “For these, there was—and still is—no substitute for human fetal tissue.”

…Anti-abortion groups praised the new policy, which would “separate federal research funding from the abortion industry”, said Melanie Israel, a research associate at the conservative Heritage Foundation… Yet how the new Trump research policy would reduce abortions is still unclear. “They are conflating pro-life issues and abortion with research”, said Jennifer Zeitzer, public affairs director at the Federation of American Societies for Experimental Biology. “But there’s no evidence that women are getting abortions so they can donate fetal tissue for research.”  [Continued here.]  …

USA sets goal to end the HIV epidemic in a decade

Volume 393, Number 10172   

16 February 2019       

 

WORLD REPORT   The unexpected announcement in the State of the Union address could set the start of a realistic agenda to end HIV/AIDS in the USA, provided funds are secured. Susan Jaffe reports.

Nearly an hour into his 90 min State of the Union address, President Donald Trump called for a government-run health-care programme “to eliminate the HIV epidemic in the United States within 10 years”.

Although the president has promised to get rid of the Affordable Care Act (ACA) along with its health insurance marketplaces and Medicaid expansion, these and other policies did not appear to dampen his enthusiasm. [Continued here.]…

Gun violence research in the USA: the CDC’s impasse

Volume 391, Number 10139   

 23 June 2018

 

WORLD REPORT   Months after the Trump Administration said that there is no ban on gun violence studies, the CDC still lacks the funding to proceed. Susan Jaffe, The Lancet‘s Washington correspondent, reports.

…Appeals for immediate federal action to make schools and communities safer have so far largely gone unanswered. And legislative efforts languish in Congress, as the chairman of a key congressional committee that oversees federal health programmes has so far resisted requests by its Democratic members to hold hearings on preventing gun violence [continued here].…

After a weekend of negotiations and demonstrations, shutdown disrupts health agencies

Susan Jaffe | Washington Correspondent for The Lancet | 22nd January 2018

On the first anniversary of Donald Trump’s inauguration as the 45th president of the United States on January 20, 2018, the federal government ground to a shutdown and hundreds of thousands of women and their supporters rallied against the new president in dozens of cities across the country. [Continued here.]  

 

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High stakes for research in US 2018 budget negotiations

Volume 390, Number  10099
 9 September 2017

WORLD REPORT    As Congress considers how to fund the government next year, scientists hope spending for research will not be curtailed. Susan Jaffe, The Lancet’s Washington correspondent, reports.  

The dramatic defeat of the Republicans’ Affordable Care Act (ACA) repeal legislation still looms over the US Capitol as Congress reconvenes this month for more tough decisions, including many that will affect health and science research programmes.  …The prospects for science funding will depend on competing budget pressures and political fissures. “There are a lot of moving parts and a lot of uncertainty”, said Matt Hourihan, at the American Association for the Advancement of Science. “And while a spending deal [agreement] is certainly possible, it’s hard to see how they get there from here.” [Continued here]…

Science appointments in the USA

  Volume 389, Number  10088
    24 June 2017

WORLD REPORT    Slow appointments and vacant positions in federal agencies challenge the stability of research in the USA.   Susan Jaffe, The Lancet’s Washington correspondent, reports.  

     As President Donald Trump rolls out his domestic agenda, his proposed budget cuts and lingering vacancies in key federal agencies have rattled some people in the biomedical research and science community.
     “This has been the most anxious time in science that I have seen in this country”, said Rush Holt, chief operating officer at the American Association for the Advancement of Science (AAAS), which represents 250 scientific societies and academies serving 10 million members. Holt cited a litany of reasons: “fake news” that distorts science, “policy making based on wishful thinking rather than evidence, funding proposals that are nonsensical, and unfilled positions in government agencies”.  [Continued here]  

 

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Marching for science as budget cuts threaten US research

lancet cover 2Volume 389, Number  10080 

29 April 2017 

WORLD REPORT   Americans push back against President Trump’s proposed budget cuts… Susan Jaffe, The Lancet’s Washington correspondent, reports. 

President Donald Trump is famous for his early morning Tweets and off-the-cuff remarks that can sometimes be puzzling. But what he thinks about biomedical research and basic science is quite clear in his first proposed budget for running the federal government.

March for Science, Washington, D.C. / Susan Jaffe

Trump’s America First: A Budget Blueprint to Make America Great Again outlines a $1·1 trillion spending plan that would take effect when the new fiscal year begins in October. The president wants to move $54 billion from domestic agencies to fortify the US military. To help pay for the transfer, he is proposing funding cuts for the US Environmental Protection Agency (EPA; 31%) and the National Institutes of Health (NIH; 18%) [and other domestic agencies]….

To squeeze $5·8 billion out of the agency’s $30·3 billion budget, the Trump administration would reorganise NIH’s 27 institutes and centres and “rebalance federal contributions to research funding” according to the budget blueprint. …Health and Human Services Secretary Tom Price told a congressional committee last month that the NIH could operate on a tighter budget by cutting the roughly 30% of grant money that pays for indirect research costs. These expenses can include rent, utilities, administrative staff, and equipment. “That money goes for something other than the research that’s being done”, Price said.

Price’s suggestion was especially disturbing coming from the person who is responsible for overseeing the NIH, said Harold Varmus, who directed the NIH in the 1990s and headed the National Cancer Institute at NIH for 5 years until 2015. “You can’t do research in the dark”, he said. “You can’t do research—at least my kind of research—without a building and without electricity and water and administrative expenses”. [Continued  here]

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Experts confident of congressional funding for US Cures Act

lancet cover 2
Volume 389,  Number 10065
14  January 2017

How future funding for the landmark 21st Century Cures Act and repeal of the Affordable Care Act may affect its success.  [Interviews with lead sponsors Representatives Fred Upton, Diana DeGette, NIH Director Francis Collins, and patient advocates.  Full article here] …

Biomedical research bill becomes law, but critics raise concerns over long-term implementation

Susan Jaffe | Washington Correspondent for The Lancet | 14 December 2016

The 21st Century Cures Act that President Barack Obama signed into law this week dedicates – but doesnthe-lancet-usa-blog-logo1‘t guarantee – billions of dollars to accelerating the discovery of new drugs and medical devices and getting them to patents more quickly, as well as supporting opioid addiction treatment and reforms in mental health care.

President Barack Obama signs the 21st Century Cures Act, Tuesday, Dec. 13, 2016. (Photo by Susan Jaffe)

The overwhelming support for the law marks a stark contrast from the Affordable Care Act, another landmark health reform bill Obama signed in the second year of his presidency.  Republicans promise to repeal it as soon as the new Congress convenes next month and Donald Trump is sworn in as president. But before the promised elimination of the ACA, Congress took nearly $5 billion from its Prevention and Public Health Fund to pay for most of the law.[Continued here.]

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US global health leadership hangs on election result

lancet cover 2Volume 388, Number  10055 

22  October 2016 

WORLD REPORT   On most issues, the US presidential candidates have polar opposite views; engagement in global health is no different.  Susan Jaffe, The Lancet’s Washington correspondent, reports.

Americans will choose their next president in less than 3 weeks and yet some global health experts still wonder what would happen to the international health programmes that the USA has championed in recent decades if the Republican contender, Donald Trump, is elected. The uncertainty comes despite the Ebola virus and Zika virus threats that made global health front-page news.  [Continued here] …

US presidential candidates urged to support health research

lancet cover 2Volume 387, Number  10037 
18 June  2016 

WORLD REPORT   Advocates for medical research are eager to hear how the presidential candidates would advance the search for new treatments.  Susan Jaffe, The Lancet’s Washington correspondent, reports.

As the most tumultuous presidential primary season in recent times comes to an end, biomedical researchers, physicians, and advocacy groups want the candidates campaigning for the White House to address some of the substantive matters they worry about: National Institutes of Health (NIH) funding, advancing Alzheimer’s disease research, speeding up drug development, and a host of research related issues.

… In New Hampshire last year, the campaigns provided a preview of the kind of discussion between candidates and voters that research and patients’ advocacy groups would like. It revealed a stark difference between Clinton and Trump on funding for Alzheimer’s research and support for those caring for the 5·4 million Americans stricken with the disease. [Continued here]

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US responds to increase in Zika cases

 lancet cover 2Volume 387, Number  10030
30 April  2016 
WORLD REPORT    Health officials pursue Zika research and prepare to combat a formidable foe—the mosquito— despite uncertain funding.   Susan Jaffe, The Lancet’s Washington correspondent, reports.

Anthony Fauci

As the number of confirmed cases of people who have contracted the Zika virus increases across the globe, the growing knowledge  about this once rare infection is not reassuring. “The more we learn, the more we get concerned”, said Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases…. 

Representative Tom Cole, the Oklahoma Republican who is chairman of the House appropriations health subcommittee, said its questions about [President Barack Obama’s $1.9 billion Zika emergency funding] request are not unreasonable….“Let us do our job to make sure we do this as prudently as possible and we will get there”, he said. “Nobody thinks this is not a serious challenge”….

While clinical research and the funding debate continues, protection from the Zika virus will depend largely on avoiding the mosquitoes that carry it….

After years of cuts in federal and local funding for mosquito control, Zika is “a pretty major wake up call to rebuild those capacities”, said Lyle Petersen, director of CDC’s division of vector-borne infectious diseases. The virus is the latest “major pathogen that has come into the Americas” in recent years—after chikungunya, dengue fever, and West Nile virus—“and it won’t be the last.” [continued here]  [listen to podcast here] …

Zika response threatened by funding shortage

Susan Jaffe | Washington Correspondent for The Lancet | 14 March 2016The Lancet USA blog logo

Congress hasn’t budged in the five weeks since President Barack Obama asked Congress for more than $1.8 billion in emergency funding to deal with the Zika virus. But Zika isn’t waiting.

In the weeks since the president’s request, the number of cases of the mosquito-borne virus among people who traveled to countries where transmission has been confirmed has almost quadrupled to 193, as of March 9. It is in nearly twice as many states — 32 and the District of Columbia — with Florida, New York and Texas topping the list. In Puerto Rico, the U. S. Virgin Islands, and American Samoa, the number of cases is 174, or 19 times higher, reports the US Centers for Disease Control and Prevention.  [continued here]  …

NIH hopes funding increases will continue

 lancet cover 2Volume 387, Number  10019
13 February 2016
WORLD REPORT   The US National Institutes of Health welcomed a record budget boost that might be the start of more sustained support. The Lancet’s Washington correspondent, Susan Jaffe, reports.

The US Congress recently approved the largest single increase in funding for the National Institutes of Health (NIH) in 12 years—a US$2 billion raise that was twice as much as President Barack Obama requested. But almost as soon as NIH supporters stopped cheering, they began to worry about next year’s budget, and the challenge of a new public health threat, Zika virus.

NIH Director Francis Collins told The Lancet that the funding boost “was enormously gratifying”. But if it is “a one-hit wonder”, he said “it won’t be sufficient to take full advantage of the remarkable scientific opportunities and talent that is out there”.   [Continued here] [podcast here]

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Congress Wrangles Over Funding for Zika Research

Susan Jaffe | Washington Correspondent for The Lancet | 12th February 2016

President Barack Obama asked Congress this week for more than $1.8 billion in emergency funding The Lancet USA blog logoto respond to Zika virus and administration officials wasted no time in explaining why at four congressional hearings less than two days later.

While such Capitol Hill visits are part of the budget process, the looming virus adds a new urgency to the proceedings–though not necessarily enough to deter controversy. [Continued here]…

Budget boon for biomedical research

Susan Jaffe | Washington Correspondent for The Lancet | 31st December 2015

budget 123115The US Congress has become famous for political gridlock  but sThe Lancet USA blog logohortly before going home for the holidays, members approved a 2,009-page budget for fiscal year 2016 with generous increases for some key health and science agencies, most notably the ailing National Institutes of Health. [Continued here.]…

End in sight for revision of US medical research rules

lancet cover 2Volume 386, Number  10000 
26 September 2015
WORLD REPORT   End in sight for revision of US medical research rules US health officials expect to update 25-year-old regulations on human participation in research by the end of next year.  Susan Jaffe, The Lancet’s Washington correspondent, reports.Lancet photo 092615
After proposing massive changes 4 years ago to rules first issued in 1991 protecting people participating  in research studies, federal health officials produced yet another revision earlier this month and say the effort to update the rules is on a fast track.
The revolution in science, technology, medicine, and public involvement that has transformed biomedical research over the past 25 years might be sufficient reason for the latest update, a daunting task that began in 2009, shortly after Barack Obama became president. But now there’s another factor driving the effort. [Continued  here]
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Congressional showdown threatens NIH funding boost

lancet cover 2Volume 386, Issue 9996,  29 August 2015

WORLD REPORT    Bills providing extra funding for the National Institutes of Health while cutting other programmes could a face presidential veto.  Susan Jaffe, The Lancet’s Washington correspondent,  reports.

After years of mostly stagnant funding for the US National Institutes of Health (NIH), two powerful congressional committees that control government spending have approved separate budget bills containing record increases for the agency.
But last month, President Barack Obama’s Office of Management and Budget director Shaun Donovan wrote to the chairman of the Senate Committee on Appropriations warning that he expects the president to veto its bill. Among other reasons, Donovan said it “drastically” cuts money for public health programmes including Medicare for the elderly and Medicaid, serving low-income Americans. And it would deny funds for operating the health insurance exchanges essential to the president’s signature health reform law, the Affordable Care Act. [Continued in full text or PDF ]
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21st Century Cures

lancet cover 212 August 2015
A dispatch from our Washington correspondent on the sluggish progress of the 21st Century Cures Act.
lancet test tubes 081215
Republicans and Democrats in the U.S. House of Representatives last month overwhelmingly passed the 21st Century Cures Act  aimed at speeding up drug development.  But the Senate is not expected to vote on its version until next year.
More than 80 percent of the House backed the legislation after it was unanimously — a word rarely heard on Capitol Hill — approved by the House Committee on Energy and Commerce.   In the process, the bill was revised to address concerns that drug approvals would happen a little too quickly, circumventing safety and efficacy standards. [Continued here]
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